Education
2000- Ph.D in Life Sciences
Division of Cellular & Molecular Cardiology, Sree Chitra Tirunal Institute for
Medical Sciences & Technology, Thiruvananthapuram, Kerala. Area of
Specialization - Biochemistry and Molecular Biology.
1985- Master’s degree in Nutritional Biochemistry,
University of Bombay, India.
experience
2004 – 2013 Oct. – As Senior Scientist, Metabolic Disorders Research Centre, Jagathy, Thiruvananthapuram.
The work mainly comprises of investigation of risk factors for metabolic disorders in our population. Evaluation of homocysteine metabolism as a risk factor for neurological & cardiac disorders is another area of interest.
Also worked in an ICMR project to delineate the effects of low cholesterol on autistic spectral disorders in children
Studies on active principles in medicinal plants like Brahmi , Tulsi etc. for neurological and cardiac disorders were also carried out in animals.
2002 – 2004 – As Senior Scientist at the Department of Biological Sciences, R& D, Terumo Penpol Ltd., Thiruvananthapuram. Research involves formulation of new products such as Intravenous Lipid Emulsion. These products were evaluated for toxicology, sterility, particle size and other biochemical parameters using experimental animals.
2001-2002 – As Research Associate at the Department of Applied Nutrition, Medical College, and Thiruvananthapuram. Supervised and carried out a project on the prevalence of Anemia in Women.
1998-2000 – As Guest lecturer in Government College for Women, engaging postgraduate students.
1995-1997 – As Research Assistant in an ICMR funded project on “Development of an Animal model for Endomyocardial Fibrosis” at the Division of Cellular & Molecular Cardiology, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Thiruvananthapuram. The work comprises of delineation of pathogenetic mechanism of endomyocardial fibrosis in rabbit model.
experience
1992-1995 as Senior Research Fellow- ICMR
Doctoral Research
Division of Cellular & Molecular Cardiology, Sree Chitra Tirunal Institute for
Medical Sciences & Technology, Thiruvananthapuram.
- To investigate the 25hydroxyvitamin D status in the population of three different
Occupational groups. - To investigate a case control study of the relationship of 25 hydroxyvitamin D3 with Coronary artery disease.
- To delineate the pathogenetic mechanism of Vitamin D induced aortic calcification by Determining 1, 25 dihydroxyvitamin D receptor in vascular smooth muscle cells using radio receptor assay.
- Histopathological studies of experimental aortic tissues using light microscopy
and Transmission electron microscopy.
The above work subsequently led to doctoral degree.
Post MSc Research
- 1990-1991 – As Junior Research Fellow at the Division of Cellular & Molecular Cardiology, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Thiruvananthapuram. Research work comprises of the determination of magnesium status in school children.
- 1986-1989 – As Research Assistant at the Dept. of Applied Nutrition, Medical College, Thiruvananthapuram in a project funded by Science, Technology & Environment, Kerala State. The study comprised the assessment of nutritional status and morbidity pattern of preschool children in Thiruvananthapuram.
Publication list
Rajasree S & Büsselberg, D. Osteoporosis: an under-recognized public health problem. J. LOCAL GLOBAL HEALTH SCI. 2016, 2 (2016).
C.C. Kartha, S. Rajasree. Vitamin D and Atherosclerosis. A noteworthy Link. In “Frontiers in Cardiovascular Health” eds. Naranjan s. Dhalla. Arun Chockalingam H. Ivan Berkowtz, Pawan k. Singal 2004. Kluwer Academin Publishers.
S. Rajasree, P.R. Umasankar, A.V. Lal, P. Sankar Sarma, C.C/ Kartha. 1,25
dihydroxyvitamin D3 receptor is up regulated in aortic smooth muscle cells during hypervitaminosis D: Life Sciences, 2002,70,1777.Rajasree, K. Rajpal, C.C. Kartha, P.S. Sharma, V. Ramankutty, C.S.P. Iyer, G. Girija. Serum 25-hydroxyvitamin D3 levels are elevated in South Indian patients with ischemic heart disease. Europ J Epidemiol. 2001,17,567-571.
S. Rajasree, V. Ramankutty, K. Sreenivasan, C.C. Kartha. Elevated serum levels of 25 hydroxyvitamin D3 in outdoor workers of South India. Current Science. 1999; 77:1136-1138.
Publication list
- R. Renuka Nair, J.T. Eapen, C. Radhakumari, S. Rajasree. Magnesium levels in serum and erythrocytes of children from Kerala. Natl Med J India. 1995; 8:118.
- S. Rajasree, C.R. Soman. Nutritional status of children in Kerala. Indian Paediatrics. 1994;31:651.
- J.T. Eapen, S. Rajasree, C. Radhakumari, R. Renuka Nair. Serum magnesium levels in school children of two socio-economic groups in Kerala. In M.S. Valiathan, K. Somers, C.C. Kartha (eds). Endomyocardial Fibrosis. Oxford University Press. New Delhi 1992. P279.
- C.R. Soman, Malathy Damodaran, S. Rajasree, V. Ramankutty, K. Vijayakumar. High
morbidity and low mortality. The experience of urban preschool children of Kerala. J. Trop Paediatrics. 1991; 17:37.
Awards and Recognition
ICMR Senior Research Fellowship – 1992-1995
Reward for best performance for productive research – 2003 from Terumo Penpol Ltd.
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